Mudgee is a wine region and Australian Geographical Indication in the Central Ranges zone in the Australian state of New South Wales. It is named for the town of Mudgee.

Grapes were first grown around Mudgee from 1858, reaching a peak of 55 vineyards in 1893. Large wineries started planting again from 1974. Mudgee grows predominantly red wine varieties, especially Shiraz, Cabernet Sauvignon and Merlot.

The town features restaurants, cafes, accommodation and regional helicopter rides for the tourist.